The natural aging process, plus genetics, is the major cause of mid-face volume loss. You may also experience volume loss because of certain medications, weight loss, stress or other lifestyle factors. As you age or are stressed the natural supports of the skin break down, and fat pads shift downward. You may notice that your cheeks are hollow, you look tired and rundown. There are solutions to bring back the plumpness to your checks and help you to lose the wrinkles and hollows causing you to look tired.