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NATURAL GROWTH FACTORS | PRF
IN SALT LAKE CITY, UT

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Bring Out Your Inner Youth

PRF at Nuance Aesthetics + Wellness

Platelet-Rich Fibrin (PRF) offers natural and effective solutions for various cosmetic procedures. One of the advantages of PRF is that it utilizes the patient's own blood, eliminating the risk of allergic reactions or rejection. Additionally, PRF offers a natural and long-lasting solution by harnessing the body's innate healing mechanisms.

At Nuance, PRF treatment offers exceptional natural results and clinical safety. While platelet-rich plasma (PRP) has been the industry standard for years, we utilize platelet-rich fibrin (PRF) because it contains more growth factors and more cells that remain active in the tissues for longer.

PRF at a Glance

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The Technology

Uses platelet-rich fibrin and human serum albumin from your own body, with no chemical additives or synthetic ingredients.

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Dual Action

Provides immediate fullness like a filler while stimulating collagen production for long-term health.

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Safety Profile

Virtually zero risk of allergic reaction since the material is derived from the patient.

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Versatile Healing

Effectively treats dark circles, marionette lines, and hair loss in a single regenerative treatment.

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The Evolution of PRF

What is PRF?

PRF ezGEL serves the purpose of skin rejuvenation and volumization. It comprises a 100% natural gel-like substance obtained from your own blood sample. Advanced technologies are employed to isolate the beneficial cells through a cooling and heating process, without the use of any chemical additives or modifications, resulting in the formation of the gel-like material. For scar revision, PRF can be applied topically or injected into the affected area to stimulate tissue regeneration, reduce scar visibility, and promote a more even skin texture. In hair restoration, PRF can be injected into the scalp to enhance hair growth, strengthen hair follicles, and improve hair density.

EZ Rejuvenation

What Is the PRF Procedure Like?

The PRF EZ Gel process begins with a small blood sample, similar to a routine lab test. This blood sample is then processed in a specialized centrifuge to separate the platelet-rich fibrin (PRF) from the red blood cells. To create the EZ Gel, a portion of your plasma undergoes a cooling and heating process to thicken the protein into a smooth, injectable gel. Once ready, the material is injected into the targeted areas using a fine needle or cannula. The entire procedure is unhurried, clinical, and centered on your comfort.

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Targeting the Signs of Depletion

PRF Treatment Areas & Conditions

PRF can be utilized in various aesthetic treatments, including facial rejuvenation, scar revision, hair restoration, and skin rejuvenation. In facial rejuvenation, PRF can be injected into specific areas to enhance skin quality, reduce fine lines and wrinkles, and improve overall skin tone. It can also be combined with other cosmetic procedures like microneedling or laser therapy for enhanced results.

Hair Restoration

If you are struggling with thinning, weak, or brittle hair, PRF injections might be the solution you are looking for! Platelet-Rich Fibrin is one of the leading treatments for hair restoration. Hair restoration with PRP will likely take 3-4 treatments to see significant improvements in hair thinning. Each appointment is scheduled 4-6 weeks apart to allow the hair to grow and the PRF to take full effect.

Scar Treatment

Platelet-Rich Fibrin can be injected or microneedled into the skin to diminish the appearance of stretch marks and superficial and surgical scarring. Treating surgical scars with PRP is an excellent option that will likely require more than one appointment to achieve optimal results. Schedule a consultation with Nuance Aesthetics today to discuss your unique case!

Facial Injections

Platelet-Rich Fibrin can be strategically injected into areas of the face to stimulate collagen production, tighten lax skin, improve overall texture, and reduce the appearance of fine lines and wrinkles. Come to your appointment hydrated and ready to have a blood sample drawn. It addresses textural issues, volume loss (like nasolabial folds and marionette lines), and can also be used to treat dark circles and "tired" eyes by improving skin quality.

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Biology Made Beautiful

What Are the Benefits of Natural Growth Factors?

Because natural growth factors like PRF contain no chemical additives or anticoagulants, they are considered the purest and safest options available in modern aesthetics. Unlike traditional plasma treatments, the fibrin matrix in PRF provides a more robust, long-lasting release of growth factors, which act as powerful biostimulator, triggering the body to produce new collagen and essential proteins.

This process doesn't just provide a temporary "fill" for a wrinkle; it fundamentally improves the health and texture of your tissues. Most importantly, the natural gel material created through the EZ Gel process integrates seamlessly with your skin, ensuring a soft, smooth, and radiant finish that honors your unique facial character.

  • Decreases wrinkles
  • Treats under-eye circles
  • Uses your body's natural cells
  • Minimal risk of side effects
  • Stimulates new collagen and skin healing
  • Improves hair loss
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“She is not only an absolute expert...”

Our Testimonials

“I have been visiting Holly for the last 8 years, and since then, I have virtually aged backwards. She is not only an absolute expert in enhancing and preserving your appearance, but she’s also incredibly knowledgeable about all things women’s health and hormones. There is NOTHING you can’t talk to this woman about! If I could stay and hang out with Holly all day, I would. Love, love, love her AND the service she provides. I almost don’t want to leave this review because once the masses discover her, she’ll be too busy for me, and I’m selfish. 😂🫣"

–Elise V., Salt Lake City, UT, hormone balancing & rejuvenation patient.

“I wouldn’t go anywhere else!”

“The staff at Nuance is the BEST, so friendly and knowledgeable! I wouldn’t go anywhere else!!”

–Missy F., Salt Lake City, UT, med spa patient.

"...beautiful results and professional expertise..."

“I highly recommend Holly at Nuance Aesthetics! She is incredibly talented and knowledgeable, making it clear from the first consultation that you are in the best hands. Every treatment she provides delivers such a natural result; she has a true gift for providing the perfect enhancement to help you age with grace. If you are looking for someone who prioritizes subtle, beautiful results and professional expertise, Holly is the absolute best.”

–Ashley M., Salt Lake City, UT, med spa patient.

"She is the only person I trust..."

“I have gone to Holly for years and love her. She is the only person I trust to help me with my Botox and hormone wellness. She is the best and such a good price. I have tried other places, and they don’t compare to her.”

–Mitzi H., Salt Lake City, UT, Botox & BHRT patient.

"These ladies are amazing."

“These ladies are amazing, and Dr. Rudy is so sweet...I have had lip filler and lip flips done at other places that left me lumpy, bruised, and boy, was it painful. Gohar recently did a full syringe, and I basically didn't feel it; my lips are perfect. Katie is an amazing injector too; she has done excellent work freezing nostrils and fixing wrinkle lines.”

–B P., Salt Lake City, UT, lip filler patient.

"Love this place!"

“Love this place! Gohar is such a pro! Very gentle and patient. I always have a great experience and outcome. 🤍"

–Danielle R., Salt Lake City, UT, med spa patient.

"...well-trained, trustworthy expert..."

“Holly is a very special person, well-trained, trustworthy expert you can trust your face to:-).”

–Corinne T., Salt Lake City, UT, med spa patient.

"Exceptional Results!"

“I’ve been coming to Nuance for several years, and my experience has always been outstanding! Injector Gohar is truly amazing—kind, gentle, professional, and genuinely caring. She takes the time to understand your needs and offers personalized advice to ensure the best results. Her expertise and attention to detail make her someone I trust completely. I highly recommend Gohar and Nuance to anyone looking for top-tier care and exceptional results! Thank you!”

–Susana G., Salt Lake City, UT, med spa patient.

"Highly Recommend!"

“Kaira is amazing, and I love getting my skin treated by her. Highly recommend!”

–Kelly B., Salt Lake City, UT, med spa patient.

"...I'm grateful to have her in my life."

“I’ve known Holly for quite a while, and I’m grateful to have her in my life. She’s been an incredible source of comfort and support when it came to my health and fertility. Her compassion and dedication to women’s health stand out. She doesn’t just offer help, she invests herself in helping you feel understood and supported. I wholeheartedly recommend her to anyone.”

–Robyn P., Salt Lake City, UT, med spa patient.

"Overall, the best experience!"

“Everyone at Nuance is so friendly and helpful. They answered all of my questions and made me feel at ease. Holly was my injector, and she is AMAZING. I didn't feel a thing, and she was so knowledgeable and honest about what she thinks I need. She would never try to upsell me on something I don’t need. Overall, the best experience!”

–Megan Van B., Salt Lake City, UT,  med spa patient.

"Friendly, courteous, understanding..."

“Gohar is amazing! Friendly, courteous, understanding, knowledgeable, confident!”

–Elnaz K.,  Salt Lake City, UT, med spa patient.

“I wouldn’t go anywhere else!”

“Love Dr. Rhudy and Staff”

–Kristin H., Salt Lake City, UT, med spa patient.

"Holly is amazing"

“Holly is amazing. She really cares and wants the very best for her clients. She is very knowledgeable and knows what she is doing. Thank you, Holly!”

–Shadalyn E., Salt Lake City, UT, med spa patient.

“I wouldn’t go anywhere else!”

“Holly is fantastic!”

–Helen K., Salt Lake City, med spa patient.

"I love Nuance Aesthetics!"

“I love Nuance Aesthetics! Kaira is an amazing aesthetician with years of experience and knowledge. She was so kind and helpful with suggestions on improving my skin health and appearance without being a pushy salesperson. The office itself is always clean and inviting. Sarah at the front desk is very knowledgeable herself and always willing to help with products and appointments!”

–Rae O., Salt Lake City, UT, med spa patient.

Your Own Natural Volume

Am I a Candidate for PRF/EZGel?

If you are looking for a 100% natural alternative to synthetic fillers, you are the perfect candidate for PRF (Platelet-Rich Fibrin) and EZGel. It is an ideal solution for patients with thin skin, under-eye hollows, or those who prefer a bio-filler derived from their own blood. Because it is autologous (sourced from your own tissue), there is virtually no risk of allergic reaction. PRF may not be suitable for patients with severe platelet disorders or those currently undergoing certain anticoagulant therapies.

The Bio-Stimulatory Phase

PRF/EZGel Recovery

There is no significant downtime after a PRF treatment, though you should expect mild swelling or a full sensation in the treated area for 24–48 hours as the gel integrates. To ensure the best results, we recommend staying hydrated and avoiding strenuous exercise or extreme heat (like saunas) for the first day. Since we use your own growth factors to trigger repair, avoiding anti-inflammatory medications like Ibuprofen for a few days post-treatment is encouraged to allow the natural inflammatory healing response to work its magic.

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Gradual, Biological Brilliance

PRF/EZGel Results

The beauty of EZGel is the two-fold transformation. You will see an immediate improvement in volume and smoothing of fine lines as the gel is injected. Over the following weeks, the PRF releases a high concentration of growth factors that stimulate your body to produce new collagen and elastin, improving the actual quality and thickness of your skin from the inside out.

While the immediate volume provides a beautiful refresh, the biological work continues for months. For the best results, we typically recommend a series of two treatments. Your rejuvenated skin quality can last a year or more, providing a refreshed look that is entirely, authentically you.

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Why Choose Nuance Aesthetics + Wellness for PRF/EZGel?

Don't Wait. Book Today.

Working with PRF and EZGel requires a high level of clinical sophistication and timing. At Nuance, we utilize advanced centrifugation protocols to ensure we capture the highest concentration of regenerative cells possible. Our team combines this cutting-edge bio-technology with a master’s eye for facial anatomy, ensuring your bio-filler is placed precisely where it will provide the most natural lift and luminosity.

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Natural Growth Factors Frequently Asked Questions

The only pain involved is with micro needling or injection. We will use numbing cream to give you more comfort.

You will start seeing Natural Growth Factor treatment results about one to two months after the treatment. Collagen will continue to build over the next year.

Those who want to rejuvenate their skin naturally would be good candidates for Natural Growth Factor treatments. However, if you have a bleeding disorder and take blood thinners, you should avoid Natural Growth Factors.

Some providers prefer Natural Growth Factors since it does not have any anticoagulants and lasts longer.

You can treat any side effects using an old compress and over-the-counter pain medication. Always use skin protection after treatment.

Natural Growth Factors have side effects of redness, bruising and pain caused by the method used. In addition, you may experience puffiness when used under the eyes, but this only lasts four to five days.

Natural Growth Factor injections are totally different. They trigger collagen products and do not add volume to injected areas.

Depending on your unique needs and the application methods used, you may need a series of treatments followed by routine maintenance treatments. Treatments will be discussed at your consultation.

There is little to no downtime with Natural Growth Factors applied topically or via injections. However, you may experience redness, swelling, and bruising, and you should avoid direct sun exposure.

Avoid non-steroidal anti-inflammatory drugs for two weeks or more before treatments. Stay hydrated and don’t consume alcoholic beverages prior to treatment.